В статье представлены данные по эпидемиологии рака предстательной желе-зы, высокая распространенность и рост заболеваемости обусловливают актуаль-ность исследований по данной онкопатологии. Показано, что увеличение числа впервые выявленных случаев связано в том числе и с программой скринингового обследования мужчин путем определения уровня простатспецифического анти-гена. Освещены современные диагностические методы выявления модифика-ций простатспецифического антигена, обладающие большей чувствительностью и специфичностью в отношении рака предстательной железы. Акцентировано внимание на изменение уровня простатспецифического антигена в зависимости от возраста, что необходимо учитывать при диагностике злокачественных ново-образований предстательной железы. Data on epidemiology of a prostate cancer are presented in article, high prevalence and body height of a case rate cause relevance of researches on this oncopathology. It is shown that the number augmentation for the first time of the taped cases is bound including to the program of a skrining of inspection of men by determination of level of prostates -a specific antigen. Modern diagnostic methods of identification of modifications of prostatesa specific antigen, possessing larger sensitivity and specificity concerning a prostate cancer are lit. The attention to change of level of prostates -a specific antigen depending on age is focused that needs to be considered at diagnostics of malignant neoplasms of a prostate.
The differential diagnostic of prostate cancer is the actual task of modern medicine. The existing methods lack accuracy and specificity. It’s the reason of hyper- or hypo-diagnostic of this disease. We developed and tested the new logistic regression model for diagnostic of prostate cancer in men of various age. The model includes age, the volume of prostate, concentration of prostate specific antigen (PCA), 2-pro-PCA in the blood, the presence of the concretion revealed during digital rectal investigation of prostate and hypoechogenic area in transrectal ultrasound investigation. The model was tested in 114 patients. It has shown the higher accuracy and specificity of the new regression model in comparison to other methods of differential diagnostic of prostate cancer.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.