2005 Bridged compounds Q 0060 Reaction of Endic Anhydride with Hydrazines and Acylhydrazines. -The products of the title reactions represent interesting synthons and possible pharmaceutical agents. -(KRISHCHIK, O. V.; TARABARA, I. N.; KAS'YAN, A. O.; SHISHKINA, S. V.; SHISHKIN, O. V.; ISAEV, A. K.; KAS'YAN, L. I.; Russ.
Derivatives. -Short reflux of equimolar amounts of aminobenzimidazole (I) with benzaldehydes (II) and dimedone (III) or with products of the intermolecular condensation of the latter, i.e. (V) and (VI), in DMF results in the regioselective formation of linearly fused benzimidazoquinazolines (IV). On the other hand, reaction of amine (I) with dimedone in the absence of benzaldehydes provides angularly fused pyrimidobenzimidazole system (VIII). -(LIPSON, V. V.; DESENKO, S. M.; SHISHKINA, S. V.; SHIROBOKOVA, M. G.; SHISHKIN, O. V.; ORLOV, V. D.; Chem. Heterocycl.
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