(Eur J Anaesthesiol. 2021;38:1052–1058) Pregnancy poses unique challenges and increased risks during general anesthesia (GA), including hypoxia. Preoxygenation helps to mitigate the risk of hypoxia in parturient women during induction of GA. High-flow nasal oxygenation (HFNO) has been suggested to improve preoxygenation efficacy. While studies have been done on HFNO preoxygenation for parturient patients, none have looked at the benefit of HFNO for the same population undergoing rapid sequence induction (RSI) GA. This study compares preoxygenation using HFNO with the standard facemask (SFM) during RSI for parturients undergoing GA for cesarean delivery (CD).

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