IntroductionUrinary tract infections are one of the most commonly seen infections in both in-and outpatient settings (1,2). In Turkey, although studies have been conducted on urinary tract infection agents and their antibiotic susceptibilities, they have generally been regional studies covering limited time periods. There are a limited number of reviews to pool the results of different studies and reveal the isolation rates of different species and their antibiotic susceptibilities in Turkey.The objective of this review is to contribute to the advancement of empirical treatment, particularly in primary healthcare settings, and to reveal the isolation rates of Enterobacteriaceae species, the most common agents of urinary tract infections, and their antibiotic susceptibilities. 2.Materials and methodsThe method used in this review was established by considering the items provided in the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols-2015 (PRISMA-P) statement. Based on this guide, information resources were identified and searching strategies were established by a team consisting of three microbiologists, one medical pharmacologist, and one biostatistician who then reviewed the studies and evaluated the data collected according to the specified acceptance/rejection criteria. Information resources to review and searching strategiesFour team members independently searched articles in the Google Scholar, PubMed and ULAKBİM-EKUAL national databases. During the database search, "Escherichia coli,