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This study aims to develop and evaluate a new Health-oriented Electronic Oral Health Record that implements the health-oriented status and intervention index. The index takes the principles of holistic oral healthcare and applies them to the design and implementation of the Health-oriented Electronic Oral Health Record. We designed an experiment using focus groups and a consensus (Delphi process) method to develop a new health-oriented status and intervention index and graphical user interface. A comparative intervention study with qualitative and quantitative methods was used to compare an existing Electronic Oral Health Record to the Health-oriented Electronic Oral Health Record, focusing on dentist satisfaction, accuracy, and completeness of oral health status recording. The study was conducted by the dental staff of the Inter-country Center for Oral Health collaborative hospitals in Thailand. Overall, the user satisfaction questionnaire had a positive response to the Health-oriented Electronic Oral Health Record. The dentists found it easy to use and were generally satisfied with the impact on their work, oral health services, and surveillance. The dentists were significantly satisfied with the Health-oriented Electronic Oral Health Record compared to the existing Electronic Oral Health Record (p < 0.001). The accuracy and completeness values of the oral health information recorded using the Health-oriented Electronic Oral Health Record were 97.15 and 93.74 percent, respectively. This research concludes that the Health-oriented Electronic Oral Health Record satisfied many dentists, provided benefits to holistic oral healthcare, and facilitated the planning, managing, and evaluation of the healthcare delivery system.

The therapeutic potency of intraperitoneally administered methocarbamol was examined against acute oral intoxication of rats caused by lethal doses of pyrethroids (fenvalerate, cypermethrin, fenpropathrin and permethrin). Methocarbamol was initially administered a dose of 400mg/kg (body weight), followed by repeated doses of 200mg/kg, when tremors or hyperexcitability to sound was observed. Methocarbamol markedly decreased the mortality; 80% mortality caused by an administration of 850mg/kg (body weight) fenvalerate to 0%, 80% mortality by 850mg/kg cypermethrin to 0%, 60% mortality by 100mg/kg fenpropathrin to 0% and 70% mortality by 850mg/kg permethrin to 10%, and it was effective in alleviating motor symptoms such as fibrillation, tremors, hyperexcitability, clonic seizures and/or choreoathetotic movements. A subcutaneous administration of 25mg/kg (body weight) atropine sulfate was also effective in mitigating salivation produced by fenvalerate and cypermethrin.

Refusal of initiation of dialysis by elderly patients with chronic renal failure Hiroshi Fujimaki1), Yutaka Kasuya2), Sachiko Kawaguchi3), Shino Hara3), Shiro Koga4), Tadao Takahashi5) and Shoichi Mizuno6)