Acne is a common human skin disease, characterized by areas of skin with seborrhea (scaly red skin), comedones (blackheads and whiteheads), papules (pinheads), pustules (pimples), nodules (large papules) and possibly scarring. Acne affects mostly skin with the densest population of sebaceous follicles. These areas include the face, the upper part of the chest, and the back. Objectives: To determine the association between various psycho-social factors and acne. Design:Population based Case-Control Study. Place & Duration:Galvera Village, Lahore from May 2019 to July 2019. Subjects & Methods. A population based case-control study with 1:1 case to control ratio was conducetd. A total of 100 persons (50 cases and 50 controls) were recruited in the study. Selection was made on laid down criteria from adult population living in rural community of Lahore after taking due consent. Interviews were conducted through a pretested questionnaire by a 10 membered team of group 01, 4th year MBBS students of Rashid Latif Medical College, Lahore under direct supervision of Department of Community Medicine, Rashid Latif Medical College (RLMC). Data was collected, compiled and analyzed through SPSS version 25.