The stomach is the most common site of gastrointestinal stromal tumors (GISTs), representing 60% to 70% of all GIST tumors of the gastrointestinal tract. Gastric GISTs are usually asymptomatic discovered incidentally during endoscopic or radiological investigations. A small percentage may present with melena, hematemesis, and anemia due to recurrent bleeding. We report a case of a giant gastric GIST presented with anemia, that successfully treated with laparoscopic resection.