1,3‐Thiazolo[4,3‐a]isoquinoline and 1,3‐thiazolo[3,4‐a]quinoline derivatives were generated by using four component reactions of acid chlorides, potassium thiocyanate, alkyl bromides, and isoquinoline or quinoline in the presence of catalytic amount of nanoparticles of ZnO at room temperature under solvent‐free conditions in good yield.
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