Background: Ventilator Associated Pneumonia (VAP) is a common syndrome in pediatrics primarily in infants and early childhood. Mechanical ventilation is one of the leading supportive modalities of management in the intensive care unit, but it conveys a lot of threats and complications. This study aimed to assess the impact of nursing guidelines on nurses’ knowledge and performance regarding to prevention of ventilator associated pneumonia in neonates through the following: 1) Assessment of nurses’ knowledge and performance regarding to prevention of ventilator associated pneumonia in neonates. 2) Designing, implementing and evaluating the impact of nursing guidelines on nurses’ knowledge and performance regarding to prevention of ventilator associated pneumonia in neonates.Methods: Research design: A quasi-experimental design was utilized to conduct this study.  Settings: The study was convoyed at Maternity & Gynecological and Children’s Hospitals affiliated to Ain shams University Hospitals from neonatal intensive care units. Sample: A convenient sample method of forty three (43) nurses, and fifty (50) neonates’ infants on mechanical ventilation was included in the study as a single study group. Tools: The questionnaire format, the observation checklist and implementation of nursing guidelines was assessed the nurses’ knowledge and performance regarding to prevention of ventilator associated pneumonia in neonates. The implementation of nursing guidelines was premeditated as reference guidelines for nurses.Results: There were statistically significant differences between mean scores of the pre and post test as regards nurses’ knowledge and performance regarding to prevention of ventilator associated pneumonia in neonates.Conclusions: Application of the nursing guidelines has a positive outcome on improving nurses’ knowledge and performance regarding to prevention of ventilator associated pneumonia in neonates. Recommendations: The current study recommended that directing a written protocol for prevention of ventilator associated pneumonia in neonates to support satisfactory knowledge, and competent practices are actually required at neonatal intensive care units.

Background: Epilepsy is the most common chronic neurological condition and very serious among adolescents. Aim: The study was aimed to evaluate the effect of educational program on frequency of epileptic attacks and self-efficacy for adolescents. Through the following: assessing adolescents' knowledge with epilepsy and frequency of epileptic attacks, designing, implementing and evaluating the effect of epilepsy teaching booklet on self-efficacy for adolescents' with epilepsy. Methods: A quasi-experimental (pre/post-test) design was utilized to conduct this study at Students' Hospitals affiliated to South Valley University Hospitals, in Qena. A purposive sample of 60 adolescents with age ranged from 12-18 years of both sexes, had a history of epilepsy at least for 6 months duration, and free from sever communication or cognitive impairment was included in the study as a single study group. Three tools were utilized in this study: the first tool was structured interview questionnaire, it had two parts; interview questionnaire sheet to assess the adolescents' sociodemographic characteristics and clinical data about epilepsy. The second tool was Epilepsy Knowledge's Scale (EKS), and the third tool was Epilepsy Self-efficacy Scale (ESES).Teaching booklet was premeditated as reference for adolescents. Results: There were statistically significant differences between mean scores of the pre and post implementation of the educational program as regards adolescents' knowledge regarding frequency of epileptic attacks and self-efficacy with epilepsy. Conclusions: there were a lack of adolescents' knowledge of epilepsy and frequency of epileptic attacks before implementing the teaching booklet of adolescents' self-efficacy. While, there were an improvement in the adolescents' knowledge was observed after implementation of the teaching booklet which had a positive effect on improving the adolescents' knowledge as regards minimizing and control frequency of epileptic attacks and maximizing adolescents 'self-efficacy. The study recommended a periodically educational program planned and offered on regular basis for adolescents' with epileptic attacks.

Context: Catheter-related bloodstream infections are the most common type of nosocomial infections among those populations. Central line-associated bloodstream infection (CLABSI) is a preventable complication of the use of CVC. Aim: This study aimed to evaluate the effect of the care bundle education program on nurses' performance regarding central line-associated bloodstream infections in high-risk neonates. Through the following: assessing nurses' knowledge and performance regarding central line-associated bloodstream infection in high-risk neonates, designing, implementing and evaluating the effect of the care bundle education program on nurses' performance regarding central line-associated bloodstream infection in high-risk neonates. Methods: A quasi-experimental (pre/post-test) design was utilized to conduct this study at neonatal intensive care units affiliated to Ain Shams University Hospitals and Teaching Hospitals in Cairo. A convenient sample of forty-five 45 nurses was included in the study as a single study group. A structured interview questionnaire, nurses’ observation checklists were used to evaluate the effect of care bundle education on nurses’ performance regarding central line-associated bloodstream infection in high-risk neonates. The care bundle education program was premeditated as reference guidelines for nurses. Results: There were statistically significant differences between mean scores of the pre and post-test as regards nurses’ knowledge and practices regarding central line-associated bloodstream infection in high-risk neonates. Conclusion: The study revealed an unsatisfactory knowledge as well as an incompetent practice among nurses regarding central line-associated bloodstream infections in high-risk neonates before the care bundle education program. The research hypotheses are supported, and the care bundle education program achieved a significant improvement in nurses’ knowledge and performance regarding CLABSI in high-risk neonates. The current study recommended establishing educational centers in all hospitals for educating and updating the knowledge and performance of new nursing staff working in NICUs and supporting them by instructional brochure and illustrative booklets.