Aim: Malignant renal tumour is a relatively rare type of cancer that occurs third in urological tumours after prostate and bladder cancers. Little is known in the literatures about its existence in Sokoto which prompted this research. This study was carried out to determine the prevalence and histopathological pattern of malignant renal tumours in Sokoto, Nigeria. Methods: A total of 11,554 H&E stained sections were reviewed from 2001 to 2012. Patient's data such as age and sex were analyzed from 36 samples which were confirmed for renal tumours. Result: Nephroblastoma has the highest occurrence in malignant cases (48.4%) followed by renal cell carcinoma (41.9%) and transitional cell carcinoma (9.68%). It was observed that nephroblastoma (15 cases) was most prevalent in the 0-7 year age group showing it is a childhood tumour, while the other ones occurred mostly in the adults. Conclusion: Nephroblastoma has the highest occurrence in malignant renal cases in Sokoto, Nigeria.
Background:Cervical cancer is the most common genital tract malignancy in the developing countries of the world. Interestingly, it has a pre-invasive stage, which can be detected through screening. The etiological organism of the disease is the human papilloma virus (HPV) that is sexually transmitted and sexually transmitted infections play a major role in the causation of infertility in developing countries.Aim:The aim of this study is to determine the prevalence of abnormal cervical smear among infertile women at Usmanu Dan-Fodiyo University Teaching Hospital (UDUTH) Sokoto, Nigeria.Materials and Methods:This is a cross-sectional study involving the assessment of cervical smears taken from infertile women attending the gynecological out-patient clinic of UDUTH sokoto over a 12-month period. cross-sectional study involving the assessment of the cervical smears taken from infertile women attending the gynecological out-patient clinic of UDUTH Sokoto over a 12-month period. Statistical analysis of the results was carried out using the EPI-INFO 3.5.1 (CDC, Atlanta Georgia, USA). Chi square test was used for association at p-value< 0.05 at 95 % confidence intervalResults:A total of 162 patients were screened during the study period. Their ages ranged from 15 to 46 years with a mean of 27.9 (6.2) years and modal age of 25-34 years. Majority of the subjects 88/159 (55.4%) were in the lower socio-economic class and 75/159 (47.2%) of the women were nullipara. Out of the 159 subjects with adequate smears, 58/159 (36.8%) were normal while 44/159 (27.8%) had inflammatory lesions. Cervical intraepithelial lesions were observed in 18/159 (11.3%) of the smears while 25 (15.7%) had evidence of HPV infection.Conclusions:Considering the relatively high incidence 18/159 (11.3%) of cervical intraepithelial lesions seen among the subjects, there is the need to integrate cervical smear in the general infertility work-up.
Background: Breast cancer is one of the most important tumours affecting women in Nigeria and all over the world, with high morbidity and mortality if detection is delayed. Objectives: This study was carried out to review the histology of all breast biopsies sent to Histopathology Laboratory in UDUTH. Method: Using haematoxylin and eosin staining method, breast biopsies received from January 2002 to December 2011 were analyzed. Demographic data such as age, sex, site of the biopsy of all the patients were obtained through histology request card and biopsy registers. Result: A total of 788 breast samples were received during the period under review, 403 samples (51.1%) were benign lesions, 256 samples (32.5%) malignant lesions and 61 samples (7.7%) are inflammatory lesions. The age group with the highest occurrence of breast pathology is 20-29 years which are mostly benign lesions, with 50-59 years age group having the highest occurrence of malignant lesions. Conclusion: The study indicated that most breast lesions occurring in the first three decades of life are benign, while those in the elderly are mostly malignant. We recommend strong awareness among the populace to encourage early detection of these lesions.
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