Background: The aim of this work is study the relationship between sperm parameters, anti-sperm antibody and some cytokines levels for infertile men. Semen samples were studied for 88 infertile men;of these (28) infertile men with normozoospermic, (29) with oligozoospermic and (31) with asthenozoospermic ,samples were collected from Fertility Centre in Al-Sadder teaching hospital in Al-Najaf / Iraq during the period of (2/11/ 2021) and (5/2/2022). All participants underwent seminal analysis and measurement of seminal plasma antisperm antibody and some cytokine. The result of the study showed negative correlation between antisperm antibody and of interleukin (IL-1and IL-6) with sperm parameter and posative correlation with leucocytes. The presence of leucocytes in the semen is associated with an increase in levels of interleukin (IL-1and IL-6) in the seminal plasma of infertile men. The presence of antisperm antibody and interleukin (IL-1and IL-6) in the seminal plasma is associated with a negative relationship in the semen quality of infertile men.

viscosity of semen is one of the important factors in the occurrence of fertilization. Increasing the viscosity leads to infertility because it affects the function of the sperm, it linked to a decrease in the movement of sperm, and thus prevents the passage of sperm through the female reproductive system naturally. The aim of this study was to assess the effect type (normal or abnormal) and severity of semen viscosity (mild, moderate, sever) on semen quality, antisperm antibody, some cytokines and zinc levels for infertile men. The study included of eighty-eight (88) semen samples from individuals that are in abstinence for 2-7 days where the study included 34 men had normal semen viscosity and 54 men had abnormal semen viscosity from Fertility Centre in Al-Sadder teaching hospital in Al-Najaf / Iraq during the period of (2/11/ 2021) and (5/2/2022). The results of current study showed a nonsignificant decrease at (p<0.05) in sperm parameters. while showed a nonsignificant increase at (p<0.05) in leucocytes in group abnormal semen viscosity as compared with group normal semen viscosity also in sever semen viscosity compared to moderate semen viscosity.