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Tuberculosis is an established cause of pyrexia of unknown origin and can implicate practically any human organ system. Splenic involvement is common in disseminated or miliary tuberculosis following hematogenous spread, but isolated splenic involvement is a very rare phenomenon. We report the case of a 30-year-old immunocompetent female who presented with high-grade fever and dull aching pain in the left hypochondrium for three months. Laboratory data provided no diagnostic information. Abdominal ultrasonography revealed an enlarged spleen with multiple small hypoechoic lesions that were corroborated on computed tomography. No pulmonary involvement or primary focus of infection was discernible elsewhere. Splenic fine needle aspiration cytology helped clinch a histopathological diagnosis of isolated splenic tuberculosis. Administration of anti-tubercular therapy resulted in resolution of the disease and an excellent outcome in our patient.

Scrub typhus is a mite-borne rickettsial disease caused by Orientia tsutsugamushi, a gram-negative coccobacilli transmitted through the bite of chigger mite. Scrub typhus has diverse clinical manifestations, often presenting either as a simple febrile illness or as a complicated multi-organ dysfunction. Neurological complications in scrub typhus are diverse but their exact incidence is unknown. Cerebellitis is another rare neurological manifestation associated with scrub typhus. Here, we report the case of a 26-year-old woman with serologically confirmed scrub typhus presenting with fever and gross cerebellar dysfunction. MRI was normal. She was managed with antimicrobials and made an uneventful recovery.

The negative environmental implications of real estate projects are one of the industry’s largest challenges. During construction, environmental consequences occur. Many threats to the ecosystem are human made, such as the ones occurring due to construction projects. That’s why this study’s purpose is to determine the country’s biggest environmental impacts. An examination of the literature discovered 28 environmental consequences of real estate construction which are subdivided into three fundamental types of repercussions was cross-sectional surveyed. A total of 48 building specialists were picked at random for questioning. Based on these experts response, the most serious environmental concerns were ranked. The relative importance index was used for ranking the discovered impacts (RII).The study concluded that real estate projects causes dust, social disruption, noise pollution, and energy usage. Construction workers were more prone to lung and organ cancer, hypertension, irritability, and insomnia, as well as other heart-related concerns. Some of the remedial measures to overcome these issues might include requiring institutions to complete environmental impact assessments (EIA). Results of the study can assist decision-makers in identifying significant environmental implications of construction and developing environmentally friendly building plans early on. KEYWORDS: Environment, Construction, Ecosystem, Pollution, Public Impact

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