While dynamic nuclear
polarization based on photoexcited triplet
electrons (triplet-DNP) has the potential to hyperpolarize nuclear
spins of target substrates in the low magnetic field at room temperature,
there has been no triplet-DNP system offering structural rigidity
and substrate accessibility. Here, we report the first example of
triplet-DNP of nanoporous metal–organic frameworks. Accommodation
of a carboxylate-modified pentacene derivative in a partially deuterated
ZIF-8 (D-ZIF-8) results in a clear 1H NMR signal enhancement
over thermal equilibrium.
This Feature Article overviews the recently-emerged materials chemistry of triplet dynamic nuclear polarization (triplet-DNP) towards biological and medical applications.
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