Sakae Shimizu scite author profile

Bafilomycin A1, a potent selective inhibitor of vacuolar H(+)-ATPase, inhibited the growth of a variety of cultured cells dose-dependently, including golden hamster embryo and NIH-3T3 fibroblasts, whether or not they were transformed, and PC12 and HeLa cells. The concentration of bafilomycin A1 for 50% inhibition of cell growth ranged from 10 to 50 nM. The dose response was nearly parallel with that of the bafilomycin A1-induced lysosomal pH increase. The degree of pH increase for growth inhibition produced by bafilomycin A1 was similar to that produced by NH4Cl in which little difference was recognized in effect among cell types.

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Metabolic products of Aspregillus terreus. VI. Metabolites of the strain IFO 8835. (3). The isolation and chemical structures of colorless metabolites.

Arai¹,

Shimizu²,

Yamamoto³

1981

CHEMICAL & PHARMACEUTICAL BULLETIN

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Metabolic products of Aspergillus terreus. IV. Metabolites of the Strain IFO 8835. (2). The isolation and chemical structure of indolyl benzoquinone pigments.

Arai¹,

Masuda²,

Kiriyama³

et al. 1981

CHEMICAL & PHARMACEUTICAL BULLETIN

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Sakae Shimizu

Energy dependence of analyzing powerAyand cross section forp+dscattering below 18 MeV

Analyzing powers ofp+dscattering below the deuteron breakup threshold

Inhibition of cell growth by bafilomycin A1, a selective inhibitor of vacuolar H+-ATPase

Metabolic products of Aspregillus terreus. VI. Metabolites of the strain IFO 8835. (3). The isolation and chemical structures of colorless metabolites.

Metabolic products of Aspergillus terreus. IV. Metabolites of the Strain IFO 8835. (2). The isolation and chemical structure of indolyl benzoquinone pigments.

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