This paper deals with actuator fault diagnosis of neutral delayed systems with multiple time delays using an unknown input observer. The main purpose is to design an observer that guarantees the asymptotic stability of the estimate error dynamics and the actuator fault detection. The existence conditions for such an observer are established. The main problem studied in this paper aims at designing observer-based fault detection and isolation. The designed observer enhances the robust diagnosis performance, including rapidity and accuracy, and generates residuals that enjoy perfect decoupling properties among faults. Based on Lyapunov stability theory, the design of the observer is formulated in terms of linear matrix inequalities, and the diagnosis scheme is based on a bank of unknown input observers for residual generation that guarantees fault detection and isolation in the presence of external disturbances. A numerical example is presented to illustrate the efficiency of the proposed approach.Key Words: Neutral system with multiple delays, unknown input observer, fault detection and isolation (FDI), linear matrix inequality (LMI).

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