Aim: To assess and compare accuracy of the clinical indications and histopathological diagnoses from hysterectomy specimens in Zaria. Methods The clinical indications comprised non-neoplastic-47 (14.8%) and neoplastic-226 (71.3%) causes. The commonest benign neoplastic indication was uterine fibroid 196 (61.8%). Malignant neoplastic indication included cervical cancer 12 (3.8%) and endometrial cancer 6 (1.9%). Cervical intraepithelial neoplasia (CIN), a preneoplastic lesion accounted for 44 (13.9%). Histopathological diagnosis of leiomyoma was made in 218 (68.8%), cervical cancer -20 (6.3%) and . Incidental pathologies seen included chronic patients were at variance with histological diagnosis. Conclusion:The clinical indication for hysterectomy and histopathological outcome are comparable in over 90% of cases. The commonest indication and histological finding in our setting is leiomyoma.