A convenient synthesis of the traditional medicine constituents magnolamide, lobechine and funebral is described. Construction of the 2‐formylpyrrole core of these natural products was achieved by means of a Maillard reaction, involving condensation of the sugar surrogate, dihydropyranone 9, with the requisite primary amines. This approach offers a very direct and general route to the 2‐formylpyrrole ring system.

A Maillard Approach to 2-Formylpyrroles: Synthesis of Magnolamide, Lobechine and Funebral. -(YUEN, T.-Y.; EATON, S. E.; WOODS, T. M.; FURKERT, D. P.; CHOI, K. W.; BRIMBLE*, M. A.; Eur.