MATERIALS AND METHODSThis was a retrospective analysis of adult patients referred to the Liver Diseases Outpatient Program at the Health Sciences Centre, Winnipeg, Manitoba, Canada between 1987 and 2015. A total of 3057 patients had serum ceruloplasmin levels documented during

A self-reported period of abstinence in excess of six months was associated with an increased risk of subsequent relapse following a hepatologist's instructions to remain abstinent. These counter-intuitive findings should be confirmed by larger, prospective studies.