Aim of the work and case presentation: This article is to present the evidence of hyperostosis frontalis interna (HFI) in a young adult male, approximately (25-26) years old, recovered from a second dynasty site (2890-2650 BC) at Tarkhan in the south of Dahshur-Egypt.HFI is rare in historic populations. It is most commonly found among females with prolonged estrogen stimulation. Males with hormonal disturbances like primary hypogonadism were found to manifest with HFI.Conclusion: This study is a further contribution to the case history of HFI in osteoarcheological studies. Further researches are recommended to have an overview on such an old disease in Egypt.