Understanding hand surgeon online ratings and identifying factors associated with positive ratings are important for both patients and surgeons because of the recent growth in physician-rating Web sites.

There was a low degree of correlation among online websites for surgeon ratings. Female surgeons and those with fewer years in practice appear to have higher ratings on these websites; comment content analysis suggests that high and low ratings are influenced by perceived surgeon competence and affability.

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Background: Matrilin-3-deficient mice exhibit increased chondrocyte hypertrophy and early osteoarthritis. Results: Matrilin-3 binds bone morphogenetic factor-2 (BMP-2) and inhibits downstream BMP-2 signaling. Conclusion:The biological function of matrilin-3 involves modulating BMP-2 pathway activity. Significance: This is the first demonstration that matrilin-3 regulates chondrocyte hypertrophy as a BMP-2 antagonist in cartilage.