BACKGROUND:The biomechanical behavior of dental implants differs from that of natural tooth which results in subsequent complications. The mechanism of stress distribution and loaditransferitoitheiimplantboneiinterfaceiisiaicriticaliissueiaffectingitheisuccessiratesiof implants. AIM OF THE STUDY:This study aimed to evaluate the difference in stress/strain distribution initheiboneisurroundingiimplantsiresultingifromitheiuseiofithreeidifferentisuperstructureimaterialsiusingistrainigaugeianalysi MATERIAL AND METHODS: Polyurethane test block was used as a bone alternative; 2 bone level implants were inserted through a surgical guide into the blocks. Three-unit FDP frameworks were fabricated using three materials: group I: CAD/CAM BioHPP, group II: CAD-CAM zirconia and group III: metal framework FPDs. Vertical occlusal load was applied gradually at a constant rate of 1N per second up to a maximum of 150 N. The resulting strain around Implants was measured by strain gauge device. RESULTS: The lowest mean (SD) micro-strain value was recorded for group I: BioHpp, followed by group II: zirconia, and the highest mean micro-strain value was found in group III: metal; a statistically significant difference was found between group I (BioHPP) and group III (metal). However, no statistically significant difference was found between group I (BioHPP) and group II (zirconia). CONCLUSION: Using BioHPP as a more resilient superstructure material had little effect on decreasing the stresses generated around dental implant.