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Adenoid cystic carcinoma is a malignant tumor involving the salivary glands, rarely developing in the nasopharynx. It is a slowly evolving entity with strong local aggressiveness and a high tendency to recurrence. We report the case of 23-year-old patient with adenoid cystic carcinoma of the nasopharynx presenting with exophthalmos in which radiation therapy is the sole therapeutic option.

Splenic metastasis is extremely rare, and neuroendocrine tumor of the stomach represents one of the rarest primary sources. The present study aimed to describe a rare case of an endocrine tumor of the stomach revealed by a splenic metastasis. We report a rare case of a 40 -year-old who presented a pain in her left hypochondriac, associated to sensation of heaviness. Abdominal ultrasound showed splenomegaly with a large lobulated hyperechoic mass associated to splenic vein thrombosis. A magnetic resonance imaging (MRI) confirming the splenomegaly, containing a large lobulated and heterogeneous mass occupying the almost totality of this organ and invading the venous system. The histological study of this splenic mass demonstrated to secondary splenic location of a grade 1 neuroendocrine tumor. As part of an investigation for a primary tumor, fibro scopy was performed and revealed an ulcerating-bourging fundic process with a histological study in favor of a grade 1 neuroendocrine tumor.

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