This study was conducted to find the potential of Thuja occidentalis (crude powder) in promoting the rate of recovery following the sciatic nerve injury in a mouse model. Thuja occidentalis was administered orally at a dosage of 2g/kg body weight. The motor functional recovery was measured using muscle grip force, sciatic functional index (SFI), and muscle weight. While the hotplate test and formalin test were performed to measure the recovery of sensory functions. Other biochemical tests were performed to analyze oxidative stress. We noted an early recovery of motor functions in the treatment group as determined by SFI (P<0.001) and grip strength test (P=0.01). Additionally, the mass of Gastrocnemius (P=0.04) and the Tibialis anterior (P=0.008) muscle was also recovered in response to the treatment. Similarly, it significantly expedites the recovery of sensory function as checked by the hotplate test (P=0.005). Moreover, the reduced oxidant status (P=0.03) and elevated antioxidants capacity (P=0.005) were also found in the treatment group. Collectively, all of these findings highlight that the Thuja occidentalis possesses the potential to accelerate functional recovery. The enhanced antioxidant capacity and reduced oxidants status of the biological system appears the possible reason for this improved functional regain after the sciatic nerve crush. Keywords: Peripheral nervous system, nerve injury, oxidative stress, sensorimotor functional regain, Thuja occidentalis.
This review is done for elaborating social and economic importance of honey bees. Honey bees are imperative natural source of many products including Honey, wax, and Royal jelly. Beside this their role in ecosystem is very astonishing including pollination service that is very obligate for our food production as well as earning from agriculture sector. Beekeepers manage the honey bees either for bee products or for pollination but principally their main endeavor is earning. Apiculture can generate enormous revenue for developing countries especially for rural population in present financial crisis. For this reason, good beekeeping practice, skill and bee disease management is required for better production. Women can also run this business as a helping hand with men. If we emphasis on this ecofriendly culture, we not only conserve honey bees and stable ecosystem, but we can increase profit as well.
Submission of an original paper with copyright agreement and authorship responsibility.I (corresponding author) certify that I have participated sufficiently in the conception and design of this work and the analysis of the data (wherever applicable), as well as the writing of the manuscript, to take public responsibility for it. I believe the manuscript represents valid work. I have reviewed the final version of the manuscript and approve it for publication. Neither has the manuscript nor one with substantially similar content under my authorship been published nor is being considered for publication elsewhere, except as described in an attachment. Furthermore I attest that I shall produce the data upon which the manuscript is based for examination by the editors or their assignees, if requested.Thanking you.
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