Owing to their varied bioactivities exhibited by Cassia fistula, efforts have been made from time to time to generate libraries of these isolated compounds and screen them for potential biological activities. MATERIALS AND METHODS Plant Material The plant material (Leaves) of Cassia fistula was collected from Mathura, Uttar Pradesh, India in the month of January 2008. It was identified by NISCAIR, New Delhi, Ref. no. NISCAIR/RHMD/Consult/2008-09/1145/177. Leaves of Cassia fistula were dried in shade and reduced to coarse powder for extraction, isolation and characterization of chemical constituents.

Introduction: Eucalyptus globulus Labill synonym blue gum tree (Family: Myrtaceae) is an evergreen tree, one of the most widely cultivated trees native to Australia, South Africa, India and Southern Europe. The bark was used against toothaches and gum aches.The leaves were used against headaches which occured on one side of the head. Eucalyptus globulus Labill synonym blue gum tree (Family: Myrtaceae) possess antidiabetic, anti-inflammatory, antibacterial, antimalarial and Antioxidant properties. Methods: The present study will assist in standardization parameters like morphological characters, microscopic evaluation, physicochemical evaluations (loss on drying, ash values, extractive values), preliminary phytochemical screening and TLC chromatographic profile of the extract were carried out and the quantitative parameters were reported. Results: Chief macroscopic and microscopic characters include lamina with secretory cavity. Lower palisade cells, Lateral vein, secretory cavity, Spongy mesophyll, Upper palisade, stomata and with terminal clusters of sclereids. Conclusion: These studies provide referential information for correct identification and standardization of this plant material.

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Diluents are chemically inactive excipients, mostly used to make up the required bulk of solid dosage form and used up to 80% in a formulation. Various studies reported that diluents used in the solid dosage forms shows unwanted effects in body on long term and some time in short duration therapy. So, it is necessary to study the unwanted effects of diluents by researchers and production chemists before preparation of a pharmaceutical formulation to reduce the unwanted actions. Present review provides toxicological data of commonly used pharmaceutical diluents and summarizes the unwanted effects of pharmaceutical diluents on public health.

Oral dosage forms are mostly preferred route for administering drugs to patient. But due to the poor solubility many drug has limited used in oral administration. Solubility is a one of the significant factor which affects dissolution rate and bioavailability. Solid dispersion is an effective method of improving the dissolution rate of poorly water soluble drugs and hence its bioavailability. In this study will focus on various methods of solid dispersion preparation, their advantages and major challenges