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Osteoarticular tuberculosis accounts for 1-5% of all tuberculosis cases, rarely involving the wrist or hand. Wrist and hand tuberculosis usually presents with multiple carpal bone involvement with impaired wrist and hand function. Isolated involvement of the carpal bone, particularly the hamate, is very rare. We report a 12-year-old female child with isolated hamate bone involvement without any limitation of wrist function. The patient was managed conservatively on antitubercular drugs. Such a case has not been reported in the past.

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