The paper presents the most important results of the Romanian–Hungarian aerial archaeological project, i.e.the intensive topographic research of the Middle Mureş Valley. Situated between the mountains, in the widen-ing valley section various aged/high terraces were formed, providing proper conditions for human habitats.Beside the already documented stone buildings from the Roman period, observed due to the negative cropmarks – especially in 2013 – positive crop marks of settlements datable before and after the Roman periodwere observed in large variety. The simultaneous examination of the geomorphological conditions underlinedsignificant differences between the prehistoric and Roman strategies of settlement establishment.