Purpose: The purpose of this study was to introduce the main concepts of statistical testing and effect size and to provide researchers in nursing science with guidance on how to calculate the effect size for the statistical analysis methods mainly used in nursing. Methods: For t-test, analysis of variance, correlation analysis, regression analysis which are used frequently in nursing research, the generally accepted definitions of the effect size were explained. Results: Some formulae for calculating the effect size are described with several examples in nursing research. Furthermore, the authors present the required minimum sample size for each example utilizing G*Power 3 software that is the most widely used program for calculating sample size. Conclusion: It is noted that statistical significance testing and effect size measurement serve different purposes, and the reliance on only one side may be misleading. Some practical guidelines are recommended for combining statistical significance testing and effect size measure in order to make more balanced decisions in quantitative analyses.

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