Background: Obstetric and perinatal outcome is an index of health in society. Various markers are being searched so as to increase the well being of mother and fetus in pregnancy. Several Studies [12,13] have revealed an association between microalbuminuria and obstetric outcome. Microalbuminuria can be used as prognostic marker in evaluation of gestational hypertension, preterm labour, GDM, PPROM, IUGR. Objective: This study was done to evaluate whether microalbuminuria which was evaluated at late second trimester could serve as marker for adverse obstetric and neonatal outcome.
Materials and Methods:A Prospective case control study was carried out on 150 people. Urine tested for urine micro albumin and creatinine and ACR ratio was calculated. Among 150 pregnant women 27 were positive for microalbuminuria and were categorised as group A. Pregnant women without microalbuminuria were considered as group B (controls). Both group A and group B were compared for obstetric outcomes. Results: Significant association found between group A and gestational hypertension and preterm labour. Conclusion: Microalbuminuria can be used as an early prognostic marker to detect adverse obstetric and neonatal outcome. It can be done in the late second trimester (around 18-24 weeks). It is a cheap, easily available method. Presence of microalbuminuria could therefore be a warning sign for the development of gestational hypertension and preterm delivery [14] . Hence presence of microalbuminuria needs further follow up and attention and strict blood pressure monitoring along with glycemic control in order to prevent adverse obstetric outcome of pregnancy.
Objective: Preeclampsia is most commoniy encountered problem in pregnancy. The aim of the present study was to assess the levels of beta HCG in preeclampsia and normal women without hypertension. Method: This was a prospective case control study undertaken on 25 preeclamptic patients and 25 healthy antenatal women in OB-GYN Department of Rajah Muthiah Medical College, Annamalai University between the periods of 2016-2018.
Result:The mean maternal serum β-human chorionic gonadotropin levels in preeclampsia were 44463.26±30595.25miu/ml that is significantly greater than normotensives (7346.200±4479.0855 of p value< 0.001). The number of complications in the preeclampsia group are increased than the normal antenatal women group. Conclusion: Mean βhcg levels tend to be significantly more in preeclampsia than healthy pregnant mothers. The higher β hcg levels associated with more neonatal and maternal complications.
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