For citrus lemon, the most common name is lemon and it is an edible fruit. After orange, lemon is the third most signifi cant specie of citrus fruits which is cultivated more than 4.4 million ton in each year. At present, the biggest producer of lemons in the world is Argentina with 1.2 million tones. In lemon, very important natural compounds containing ascorbic acid, minerals, citric acid, essential oils and fl avonoids are present in high quantity [2]. Lemon shows anticancer and antibacterial activity due to the presence of alkaloid constituent in different parts of lemon leaves, stem, root and fl ower [3]. There are different varieties of lemon include: Avon, Berna, Baboon, Bearss, Cameron [4]. Peels of lemon consist of various phytochemicals, such as glycosides, volatile oils,  and -sitosterol. There are various signifi cant activities found in lemon like polyethoxylated, ascorbic acid, fl avones, phenolic compounds which are exceptional in other plants. In 200A.D, lemon plant was fi rst introduced in southern