Objective To observe the role of uterine artery Doppler flow velocimetry at midtrimester in prediction of preeclampsia. Method 179 women carrying \16 weeks of pregnancy, with singleton fetus and without any fetal anomaly were recruited and were divided in high-risk and low-risk group. Doppler velocimetry of uterine artery was done at 24-26 weeks. Any notch in uterine artery, unilateral or bilateral, or RI [ 0.6, was considered abnormal. Women were followed up and development of preeclampsia noted. Result Sensitivity and specificity of abnormal uterine artery Doppler study for prediction of preeclampsia were 73.33 and 86.48 % in high-risk and 57.14 and 95.83 % in low-risk group, respectively. Relative risk with 95 % confidence interval was 5.427 (2.272-12.958) in high-risk and 13.65 (5.669-32.865) in low-risk women. Conclusion Doppler velocimetry of uterine artery at 24 weeks can be used as a reliable screening test for prediction of preeclampsia in both high-risk and low-risk women.Keywords Doppler velocimetry of uterine artery Á Preeclampsia Á Screening test Á High-risk and low-risk women

Reed's syndrome or familial leiomyomatosis cutis et uteri is an autosomal dominant disorder, characterized by multiple cutaneous and uterine leiomyomas. We report here a case of a 53-year-old woman who presented to us with multiple painful nodules over different parts of her body. Based on the histopathological examination, imaging, and past medical records, a diagnosis of Reed's syndrome was made. Three of her sisters had similar disease. Subsequently, it was found that a total of nine members of their family in two successive generations were affected with cutaneous leiomyomas. The present case series has been reported for its interesting clinical presentations and rarity.

Background and aims: Lateral nasal wall of each nasal cavity provides the final common pathway of drainage of the muco-ciliary clearance of frontal, maxillary and anterior ethmoidal air cells. Anatomical variant like Concha Bullosa may obstruct the muco­ ciliary clearance thmugh osteomeatal complex and cause rhino sinusitis. The objectives were to find out the anatomical variation of middle concha and its clinical correlates with variation of middle concha. Methods: The present study was a descriptive, hospital based cross sectional study carried out in the outpatient departments of North Bengal Medical College & Hospital among 15 years and above patients. Coronal CT scan of paranasal sinus and orbit region was done. Data was collected with the help of semi structured predesigned and pretested questionnaire. Results: Of the 44 study patients, 15.9% had Concha Bullosa, 11.36% had paradoxical middle concha. Dimensions of right and left concha were also studied. 77.3%, 59.1% and 47.7% had sneezing, rhinorrhoea and headache respectively. Conclusion: The harmony of mucociliary clearance and obstruction free osteomeatal complex is the key factor for ventilation and drainage of maxillary, fmntal and anterior ethmoidal air cells.

minerva reported significantly smaller negative effects than studies not funded by the industry (American Journal of Public Health 2007;97:667-75). Overall, soft drinks are strongly associated with greater energy intake and body weight and lower intake of milk, calcium, and other nutrients as well as greater risk of medical disorders such as diabetes.