J o u r n a l P r e -p r o o f SPECIAL ARTICLE Recommendations on the management of the SARS-Co V-2 coronavirus pandemic (Covid-19) in kidney transplant patients Recomendaciones en el manejo de la pandemia por coronavirus SARS-CoV-2 (Covid-19) en pacientes con trasplante renal SUMMARY The SARS-CoV-2 (Covid-19) coronavirus pandemic is evolving very quickly and means a special risk for both immunosuppressed and comorbid patients. Knowledge about this growing infection is also increasing although many uncertainties remain, especially in the kidney transplant population. This manuscript presents a proposal for action with general and specific recommendations to protect and prevent infection in this vulnerable population such as kidney transplant recipients.RESUMEN La pandemia de coronavirus del SARS-CoV-2 (Covid-19) está evolucionando muy rápidamente y significa un riesgo especial para pacientes inmunosuprimidos y con comorbilidad.. El conocimiento sobre esta creciente infección también está aumentando, aunque Page 4 of 19 J o u r n a l P r e -p r o o f persisten muchas incertidumbres, especialmente en la población de trasplante de riñón. Este manuscrito presenta una propuesta de acción con recomendaciones generales y específicas para proteger y prevenir la infección en esta población vulnerable, como los receptores de trasplante de riñón. Palabras clave: Covid-19, trasplante renal, inmunodeprimido, SARS-CoV-2.

Visceral leishmaniasis should be suspected in renal transplant recipients in whom a fever develops of unknown origin. A 53-year-old renal transplant recipient developed pyrexia, hepatosplenomegaly, and pancytopenia 4 years after transplantation. Antileishmaniasis serology was negative, and the diagnosis was confirmed through bone marrow examination. Treatment with glucantine (N-methylglucamine antimoniate) led to acute pancreatitis, and treatment with ketoconazole plus allopurinol for 21 days was effective to eradicate Leishmania donovani.

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The evaluation of CD4CD25CD62LCD45RO aTreg cells may be useful as pretransplantation predictive biomarker of AR in kidney transplant patients. Definitive confirmation of our results awaits tests in validation groups.

A patient who received two kidney transplants was placed on hemodialysis after failure of both grafts. He had complained of abdominal pain during the preceding month and was found to have a pulsating mass in his right pelvic region. Computed tomography and color Doppler studies showed a large pseudoaneurysm of the common iliac artery. We describe the treatment of this lesion by the use of ultrasound-guided thrombin injection. To the best of our knowledge, this is the first report regarding the use of ultrasound-guided percutaneous thrombin injection for treatment of such a pseudoaneurysm.