In pediatric IBD iron anemia, the evidence supporting the efficacy and safety of IV-iron is scare. This prospective study aims to evaluate the safety and efficacy (short and long term) of IV-iron in these patients. Nineteen pediatric CD patients were evaluated before and after IV iron treatment (40-month period).The median Hb before and after IV iron was 10.5 and 12.7 g/dl, respectively. No major adverse reactions were documented. Six patients needed re-treatment (median period of 15.5 months). This study further demonstrates the efficacy and safety of IV iron. It reinforces the importance of long-term follow-up of the iron status in pediatric CD patients.

Background The COVID-19 pandemic catalyzed the adoption of home telemonitoring to cope with social distancing challenges. Recent research on home telemonitoring demonstrated benefits concerning the capacity, patient empowerment, and treatment commitment of health care systems. Moreover, for some diseases, it revealed significant improvement in clinical outcomes. Nevertheless, when policy makers and practitioners decide whether to scale-up a technology-based health intervention from a research study to mainstream care delivery, it is essential to assess other relevant domains, such as its feasibility to be expanded under real-world conditions. Therefore, scalability assessment is critical, and it encompasses multiple domains to ensure population-wide access to the benefits of the growing technological potential for home telemonitoring services in health care. Objective This systematic review aims to identify the domains and methods used in peer-reviewed research studies that assess the scalability of home telemonitoring–based interventions under real-world conditions. Methods The authors followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines and used multiple databases (PubMed, Scopus, Web of Science, and EconLit). An integrative synthesis of the eligible studies was conducted to better explore each intervention and summarize relevant information concerning the target audience, intervention duration and setting, and type of technology. Each study design was classified based on the strength of its evidence. Lastly, the authors conducted narrative and thematic analyses to identify the domains, and qualitative and quantitative methods used to support scalability assessment. Results This review evaluated 13 articles focusing on the potential of scaling up a home telemonitoring intervention. Most of the studies considered the following domains relevant for scalability assessment: problem (13), intervention (12), effectiveness (13), and costs and benefits (10). Although cost-effectiveness was the most common evaluation method, the authors identified seven additional cost analysis methods to evaluate the costs. Other domains were less considered, such as the sociopolitical context (2), workforce (4), and technological infrastructure (3). Researchers used different methodological approaches to assess the effectiveness, costs and benefits, fidelity, and acceptability. Conclusions This systematic review suggests that when assessing scalability, researchers select the domains specifically related to the intervention while ignoring others related to the contextual, technological, and environmental factors, which are also relevant. Additionally, studies report using different methods to evaluate the same domain, which makes comparison difficult. Future work should address research on the minimum required domains to assess the scalability of remote telemonitoring services and suggest methods that allow comparison among studies to provide better support to decision makers during large-scale implementation.

a r t e c i ê n c i a /a r t i g o s 25ção sem barreiras entre as disciplinas, que promova a criatividade e a inovação. A rede de educadores que abordam essa prática tem gradativamente se espalhado pelo mundo [9].No Brasil, temos um cenário ambíguo na interação entre arte e ciência. Por um lado, ainda há um grande desconhecimento do campo, inclusive no meio acadêmico. Não há praticamente nenhum investimento por parte das agências de fomento e a maior parte das instituições se limita a promover ou incentivar alguns projetos extensionistas dispersos. Por outro lado, temos pesquisadores que foram trilhando seus próprios caminhos e criando espaços e, com resiliência, têm participado da ampliação desse campo no país. Neste Núcleo Temático são apresentados exemplos de trabalhos feitos no Brasil. A pesquisadora Tania Araújo-Jorge e colaboradores tratam em seu artigo sobre os mais de 30 anos de atividades integrando ciência e arte na Fiocruz. O grupo defende essa abordagem no ensino, em todos os níveis, para a formação de cientistas e para a formação de cidadãos. No artigo seguinte, Carla Almeida e colaboradores abordam ações de ciência e teatro no campo da divulgação científica, dando destaque para as iniciativas do Museu Ciência e Vida/Fundação Cecierj e do Museu da Vida/Fiocruz, ambos no Rio de Janeiro. A partir de uma visão das artes, os pesquisadores Cleomar Rocha e Suzette Venturelli abordam em seu artigo como a arte, a tecnologia e o design podem revolucionar o conceito de cidades inteligentes, envolvendo interatividade, energia, ecologia, mobilidade, arquitetura responsável, sociabilidade e cidadania. Por fim, com a colaboração de Roger Malina e Denise Lannes, faço um retrato do universo acadêmico brasileiro que atua nessa área. Resultado de mais de dois anos de pesquisa, o artigo traz uma análise do perfil de pesquisadores que atuam na relação entre arte e ciência no país quanto à sua formação acadêmica, área de atuação, projetos e produções.

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