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The synthetic efficacy and biological relevance extend an opportunity to further drug-discovery development of fluoro-spiro-isoxazolines as novel anti-viral and anti-cancer agents.

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International audienceEnterprise architecture (EA) serves as a means to improve business-IT and strategy-operations alignment in an organisation. While it is a fairly mature domain in large enterprises, the need for EA in small and medium-sized enterprises (SMEs) has only been recently addressed. As SMEs have different characteristics and cope with specific problems, a different approach is essential to enable a successful adoption of EA. In order to meet these particular requirements of SMEs, the EA approach CHOOSE has been developed. In previous research, emphasis has been put on refining the method and metamodel of CHOOSE and on the development of supporting software tools. However, the visual notation of CHOOSE has not been investigated yet, while the form of representation has a great impact on the cognitive effectiveness of a diagram. This paper assesses the current visualisation of CHOOSE, describes alternatives and conducts an experimental comparison