Compounds containing 1,3-oxazepine and 1,3,4-oxadiazole (5)- (8) were synthesized by microwave assisted organic synthesis method through the condensation reaction of compounds (1 to 4) with phthalic anhydride respectively. The structure of the synthesized compounds were characterized by spectroscopic methods ( 1 H NMR, FTIR). The synthesized compounds were screened for their antibacterial activity disc diffusion method.

Background: Breast cancer is most common cancer in women. Obesity is one of related-risk factor in breast cancer. In obese normal subjects, alkaline phosphatase (ALP) has been studied. However, there is no previous study investigate the association between ALP and obesity in breast cancer and its correlation with other clinical characteristics. Therefore, the objective of present study is to investigate the association between ALP and clinical characteristics in generally and obesity in particularly. Methods: A cross-study 111 new diagnosed breast cancer patients was included. Plasma ALP was measured in different subgroups: patients age <40 vs >40, premenopausal vs postmenopausal, estrogen receptor-positive (ER+) vs estrogen receptor negative (ER-), metastasis vs non-metastasis and obese vs non-obese patients. Results: Significant increasing on plasma ALP were shown between groups of each age, menopausal status, metastasis, and obesity (p< 0.05, p< 0.05, p< 0.01 and p< 0.05) respectively. Positive correlation was observed between plasma ALP and age,

Asthma is a chronic worldwide disorder. Recent studies refer to association between asthma and major CVD incidence, which the abnormality of lipid profile is a direct indicator to this type of disease. The aim of this study is measuring the lipids levels in asthmatics and evaluates the omega 3 fatty acid effects on lowering its levels in asthmatics sera. Twenty five asthmatic patients (10 females and 15 males) were involved compared with 25 healthy controls. Serum samples analyzed for total cholesterol, triglycerides, high density lipoprotein, low density lipoprotein, and very low density lipoprotein. Before and after 3 weeks of supplementation of two types omega-3 polyunsaturated fatty acids (300mg/day) (4 weeks of follow up.) After 3 weeks of supplementation the change in levels of lipid profile.