Vulvar elephantiasis is a very rare condition often caused by filariasis infection. Other causes like general inflammatory disease, cancer treatment, traumatic causes or other infections can also explain the occurrence of this condition. In some cases, it is due to unknown causes. In this study, we present the clinical case of a Moroccan youth female patient with no significant history, who presented vulvar elephantiasis associated with scabies with no evidence of filariasis infection, general inflammatory disease, malignancy, or other infection. This clinical case is unusual because of the large volume of lymphedema, its atypical localisation, its association with generalised scabies, and the absence of a well-defined aetiology, which may explain its occurrence.

Introduction: Basal cell carcinoma is the most common skin cancer. It usually occurs in sun-exposed areas; perianal location is rare. The extension to the anal canal is exceptional, only a few cases were reported in the literature. Observation: We report the case of a 58-years-old patient, referred for chronic ulceration of the perianal area. Histopathology revealed an extensive basal cell carcinoma. Wide local excision was performed, with a favourable outcome. Conclusion: the main lesson from this case is that although basal cell carcinoma is exceptional in the perianal region, a biopsy is mandatory for all chronic perianal ulcerations.

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Extravasation is defined as the leakage of fluid from a blood vessel into the surrounding area at the injection site. These accidents occur during injection for diagnostic or therapeutic purposes, carried out through the peripheral or central venous lines (Chemotherapy, metabolites, or contrast agent for radiographic examination). They can be the cause of skin necrosis able to progress to significant functional, cosmetic, and psychological sequelae.  The saline washout technique is the emergency surgical treatment of choice for extravasations of certain products, allowing the elimination of the toxicant and the preservation of the skin. In the event of skin necrosis, covering techniques such as directed healing, grafts and flaps allow healing.  The difficulty of the therapeutic management of these lesions and their unpredictable evolution, require prevention, by the development of protocols for the installation and monitoring of the venous catheters, and by the continuous training of the nursing staff to know the symptoms of extravasation, and their immediate management.  The aim of this work is to present a review of the existing literature, allowing to know the diagnostic criteria, insist on the means of prevention, and propose a protocol of management.