Background: Breast lump is one of the commonest complaints with which patients present in breast clinics. As in most cases breast lump ultimately leads to a diagnosis of breast cancer, it is important for women with a breast lump to receive appropriate evaluation. So initial diagnostic approach such as utilization of rapid, inexpensive, presumptive and safe method is utmost important as such methods not only would benefit both patients and clinicians by prompting proper preoperative diagnosis and management but also further limits unnecessary testing and procedures. Aim and objectives of this study was to analyse the diagnostic accuracy of mammogram according to Breast Imaging Reporting and Data System (BI-RADS) score and fine-needle aspiration cytology (FNAC) in patients presented with benign and malignant breast lumps in authors centre.Methods: During this retrospective study from January 2018 to December 2018, the subjects concerned included all the female patients, who were referred to the department of pathology for FNAC of their breast mass and had radiological reports (mammography) with BI-RADS score according to the latest guidelines. The sensitivity, specificity, accuracy, positive and negative predictive values of BI-RADS scores and FNAC in diagnosis of breast diseases was done on the basis of final diagnosis.Results: In this study, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy was 88.57%, 82.46%,75.61%,92.16% and 84.78%, respectively for Mammography (BIRADS) score and 100% for all the parameters on FNAC.Conclusions: According to authors above study findings concluded that FNAC could be considered an ideal initial diagnostic modality in all breast lumps recognized by means of imaging techniques. It is not only considered as safe, cost effective, rapid and presumptive diagnostic method but also further limits unnecessary testing and procedures.

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Background: Lymphadenopathy is one of the most common clinical presentations and major causes of morbidity. Thus, clinical recognition and urgent diagnosis is of paramount importance. So, we aimed to analysis the diagnostic role of fine needle aspiration cytology (FNAC) in superficial lymphadenopathy in a regional cancer centre, Odisha, India.Methods: A total 1129 cases were retrieved from the hospital record retrospectively from the patients who had presented with superficial lymphadenopathy from January 2015 to December 2015.Results: Out of 1129 lymphadenopathy cases, 671 (59.43%) were male and 458 (40.56%) were female with male to female ratio 1.46:1. The age of the patients ranged from 4 years to 83 years with mean age 48.57 years. The most common site was observed in cervical lymph node 493 (43.66%) followed by submandibuar lymph nodes 198 (17.53%) and supraclavicular lymph nodes 172 (15.23%). 584 (51.27%) were malignant and 545 (48.27%) were benign. Reactive hyperplasia was most common 318 (58.34%) among benign cases where as metastatic squamous cell carcinoma was the most common 261 (50.77%) among malignant lesions. By FNAC all benign lesions were correctly diagnosed, and primary sites of malignancy identified in 442 (85.59%) cases. Cyto-histo correlation was done in 399 cases. The overall diagnostic accuracy of FNAC was found to be   93.98%, sensitivity 93.88%, specificity 94.64%, positive predictive value 99.8% and negative predictive value 71.62%.Conclusions: FNAC is a highly sensitive and specific tool for early detecting primary malignancy and metastatic lesions. Many inflammatory lesions can be treated based on FNAC alone.

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