We report a case of juvenile nasopharyngeal angiofibroma (JNA). A 19-year-old male came to our clinic complaining of severe nasal obstruction and epistaxis. Imaging investigations using computed tomography and magnetic resonance imaging techniques revealed a soft tissue mass in the nasopharynx with minimal extension to the pterygopalatine fossa. After embolization of the internal maxillary artery, we successfully performed endoscopic transnasal surgery for a JNA using an ultrasonically activated scalpel. Endoscopic follow-up for the 18 months after the surgical procedure revealed no evidence of recurrence or residual tumor.

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