COVID-19 is an infectious pandemic disease caused by the virus called as SARS-CoV-2. It is the pathogens that primarily target the respiratory system of human beings. The most common symptoms at the beginning of COVID-19 illness are, cough, fever, muscle pain, diarrhoea, headache, and Acute Respiratory Distress Syndrome occurs in severe cases. The idea of Srotas, in all different appropriate meaning, is still related in the current situation and might give different visions if revisited. Hridaya (Heart) and Mahasrotas(Gastro-intestinal tract)  and are the origins  of Pranavahasrotas (respiratory system). In the view of the current review, the introductory classical text of Ayurveda like Charak Samhita and compilation textbooks, research publication and internet sources are also reviewed to explore the relation of Pranavaha srotas and COVID-19 disease.  In the diseases of Pranavaha srotas, similar symptoms are found as it is in connection with an organ like heart, lungs, brain and Gastro-intestinal tract. The treatment protocols for diseases of Pranvahahasrotas includes general Snehan Karma(Oleation) and Swedan Karma (Sudation) therapies, Vamana(emesis), Dhumapana (medicated smoking) therapy, Rasayan  therapy(Rejuvenation Therapy), treatment of Jwar(fever) and classical formulations like Kantakari ghrita, Shrungyadi Churna, Talisadi churna, Vasa Avaleha, Kanakasava, Shwasakuthar Rasa, Mahalaxmivilas rasa etc. recommended. So current review will be useful for research on treatment protocol mentioned for the management of diseases of Pranavaha srotas given COVID-19 and also as a reference for additional safety and efficacy studies; pharmaceutical manufacturing as well as standardization of classical formulations stated for the treating diseases of Pranavaha srotas.