1,3-Dipolar cycloaddition reactions of α-chloro and simple nitrones have been studied with novel α-N-methyl/phenyl furan derivatives as new dipolarophiles. The reactions are found to be highly regioselective to afford single 5-spiro isoxazolidines with high yield in a short reaction time.

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Isoxazole derivatives R 0240One Pot Stereoselective Synthesis of Isoxazolines from N-Phenyl-α-chloro Nitrone. -(CHAKRABORTY*, B.; KAFLEY, S.; CHHETRI, M. S.; Indian J.

. -A variety of novel isoxazolidine derivatives is synthesized by regio-and stereoselective 1,3-dipolar cycloaddition reactions of nitrone (I) with maleimide derivatives (II) or olefins (V). Most of these isoxazolidine derivatives show marked antibacterial activity. -(CHAKRABORTY*, B.; CHHETRI, M. S.; KAFLEY, S.; SAMANTA, A.; Indian J. Chem., Sect. B: Org.

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