No statistically significant differences in treatment efficacy were detected between 20 Gy IF radiotherapy and 1X (COPP + ABVD) chemotherapy following CR after six cycles of alternating chemotherapy in patients with advanced-stage HD. However, limited observations in a non-randomized cohort indicate that patients without consolidation treatment of CR after 6 cycles of chemotherapy may have an elevated risk of relapse.
A Brucella canis infection, causing recurrent fever with so-called granulomatous hepatitis and splenomegaly, was detected serologically in a 30-year-old female patient. The disease originated in an infected dog from Greece which also showed a high titre. Following successful initial treatment with cotrimoxazole and streptomycin the disease broke out again on two further occasions. The infection was finally cured by 4-months continuous cotrimoxazole treatment after which the Brucella canis titre dropped from 1:1280 to 1:40 and then to zero. The patient has been symptom-free for the last two years.
Retroduodenal perforation is considered a rare but serious complication of endoscopic papillotomy. We report on a patient suffering from a stenotic occlusion of the ductus hepatico-choledochus on whom a pre-cut via needle-knife was performed in order to place a stent. Hours after the procedure, the patient developed an extensive pneumoretroperitoneum, pneumopericardium and scrotal emphysema. The later have not been reported in relevant literature so far.
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