In this study, we aimed to determine whether the presence and duration of diabetes mellitus (DM) is ‎associated with changes in intervertebral disc degeneration, epiphyseal plaque degeneration, and ‎subcutaneous fat tissue thickness. Diabetic patients and non-diabetic participants (control group) who applied to the ‎internal medicine outpatient clinic between 2020-2022 and had lumbar spine magnetic resonance imaging ‎due to low back and/or leg pain were included the study. Disc degeneration, epiphyseal plaque ‎degeneration, and subcutaneous fat tissue thickness parameters of DM patients and control group were ‎reviewed retrospectively, and the results were statistically evaluated. There were 80 DM patients in the ‎patient group, 25 (31.3%) of these patients were male and 55 (68.8%) were female. There was a total of ‎‎121 participants in the control group, of which 39 (32.2%) were male and 82 (67.8%) were female. The ‎mean age of the patient group was 57.85±10.76 years, while the mean age of the control group was ‎‎54.23±13.09 years. There was no significant difference between the duration of DM and disc degeneration, ‎epiphyseal plaque degeneration, and subcutaneous adipose tissue thickness. However, there was a ‎significant difference between the control group and the DM patient group in terms of disc degeneration and ‎epiphyseal plaque degeneration (p=0.003 and p=0.017, respectively). This study reveals that patients with ‎diabetes have an increased susceptibility to disc degeneration and epiphyseal plaque degeneration, ‎regardless of disease duration. Control and treatment of diabetic disease will make an important contribution ‎to the prevention of secondary complications‎.

ABSTRACT Objective: We aimed to show the presence of muscle-joint pain and malaise among the symptoms persisting following Covid-19 disease in regions where brucellosis is endemic. Methods: Fifteen PCR-positive patients diagnosed with Covid-19 after 1 April, 2020, in our hospital and with persisting muscle-joint pain, and testing positive with Brucella agglutination and/or Coombs agglutination 1/160 or above were included in the study. Results: Six (40%) of the patients in the study were male and nine (60%) were female. Males were between the ages of 31-69 and had a median value of 52, while females were between the ages of 38-57 and had a median value of 43. Muscle-joint pain, malaise, fatigue, fever, and sweating were frequently seen symptoms. Time to onset of symptoms in the post-Covid period ranged between seven and 220 days. Conclusion:We think that brucellosis should be considered in the differential diagnosis of patients diagnosed with Covid-19 in endemic regions ad presenting to hospital with symptoms of muscle-joint pain and malaise after treatment.

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