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The structures of decatromicins A and B that strongly inhibit the growth of MRSAwere elucidated by the analysis of various NMRexperiments. The planar structure was determined by 1H, 13C, COSY, HMQCand HMBCNMRspectra. The relative configuration of aglycone was elucidated by NOESY experiments and the absolute structure was determined by application of the modified Mosher's method. The absolute structure of glycosyl moiety was determined by X-ray analysis of the 0-(j?-bromobenzoyl) derivative.New antibiotics decatromicins A (1) and B (2) isolated from the culture broth of Actinomadura sp. MK73-NF4 have shown potent anti-MRSA activity. In the preceding paper, the taxonomy of the producing strain, production, isolation, physico-chemical properties and biological activities of 1 and 2 have been reported0. We describe herein the structure determination of 1 and 2 (Fig. 1

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