The Coronavirus pandemic has caused more deaths than any other single disease since the outbreak was confirmed. The World Health Organization in collaboration with national and international health agencies continues to lead the way in bracing global healthcare systems to fight the pandemic. There are variations in national capacities towards the preparedness and management of the pandemic. The Government of Ghana, through the Ministry of Health and Ghana Health Service, continues to provide policy and operational directions towards the containment of the pandemic. The purpose of this study is to review the setup of the healthcare sector in Ghana in light of the ongoing pandemic. This study is a narrative literature review in which data was extracted from electronic databases such as PubMed, Google Scholar, Scopus and Ebscohost that published Covid-19 research articles from Ghana. Literature was analyzed and discussed based on the structures and systems available in the healthcare sector, as well as trends available from the global perspective. The healthcare sector in Ghana continues to support the citizenry in the wake of the Coronavirus pandemic. The government provides regular updates and continue to pledge their support in dealing with the effects of the pandemic. Challenges with accessibility, workforce, funding, and infrastructure remain the major hindrances in fighting the pandemic. The government and healthcare partners need to continually reform the healthcare system to meet the increasing demand for healthcare during the pandemic.

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Background: The COVID-19 pandemic continues to adversely affect healthcare systems worldwide. Developed and underdeveloped countries continue to strive toward sustainable health policies that will help contain the spread and, at the same time, manage the patients. Global policy initiatives since the confirmation of the outbreak are guided by the recommendations from the World Health Organization. Countries, states, and territories develop domestic policies based on their capacities and resources. This study aims to provide insight into Ghana’s health policy response to the COVID-19 pandemic. Materials and Methods: This study is a narrative review of literature in which data were extracted from electronic databases such as Embase, PubMed, Google Scholar, ScienceDirect, and Web of Science that published research articles on the initial policy response to COVID-19 in Ghana. A concurrent relative search was also conducted on the websites of the Ghana Ministry of Health and Ghana Health Service to aggregate and synthesize existing policies enacted in response to the coronavirus pandemic within the first year of the outbreak. Results: Ghana’s health policy response to COVID-19 was proactive and reactive. Policy changes occurred when cases started emerging in Ghana. The focus of health policy was mainly to preserve lives. Policy implementation was a collaborative effort between public and private organizations. Conclusion: The government of Ghana, through the Ministry of Health and the Ghana Health Service, has remained at the forefront of providing policy directions to the Ghanaian people in the fight against COVID-19.