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Coined in 1961 by Hirsch and Helwig, the term chondroid syringoma refers to a rare mixed tumour of subcutaneous tissue. Histologically, these tumours are almost identical to pleomorphic adenomas, arising from salivary glands. With the obvious difference being the presence of sweat gland tissue (syringoma) within a matrix of cartilage (chondroid). These mixed tumours remain scarce throughout the world, with an incidence of less than 0.098%. The vast majority of cases are reported in middle-aged and older adults, where they typically present as painless swellings in the head and neck, which gradually grow in size.

Fig 2: Immunohistological pictures:(a) Dense diffuse dermal infiltrate consisting of large histiocytes and multinucleated giant cells showing eosinophilic 'ground glass appearance';(b) diastase resistant granules in the cytoplasm (c) Positive CD68 immunohistochemical stain (brown colour) in the macrophages (d) Positive CD45 immunohistochemical stain (brown colour) in the macrophages Author contributionsAuthor 1-Omowunmi Ashaolu-Writing-original draft preparation, review and editing.

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