INTRODUCTIONThe profession of midwifery is seen as a genuinely individual-centric catalyst transforming compassion to care. Due to this, compassionate care should be the basis of midwives' care, especially for those who care for women and children. This research investigated the compassion levels of midwives to determine the factors affecting them. METHODS This descriptive research was conducted between 10 February and 29 May 2020, with 119 midwives working in a training and research hospital in Istanbul. The data were collected using the 'Compassion Scale' and analyzed using the Mann-Whitney U test, Kruskal-Wallis test and logistic regression model. RESULTS The total mean score on the compassion scale of midwives participating in the study was found to be 71.46 ± 9.60. Sociodemographic data and vocational belongings of participants were compared with the mean scores of the compassion scale subdimensions. It was determined that as the age of the midwives increased, they showed more kindness and awareness of compassion (p<0.021, p<0.023, respectively). It has been determined that as the education level of midwives decreases, their compassion level also decreases and they become more insensitive (p<0.044). It was found that being married increased the kindness (p<0.023) and common humanity characteristics (p<0.032) that affect compassion. It was found that the levels of kindness (p<0.020) and awareness (p<0.048) increased for those who had children, and compassion was associated with having a child. In addition, a statistically significant relationship was found between the professional commitment and kindness of the midwives participating in the study (p<0.034). It was found that midwives' knowledge of rules related to professional ethics increased their compassion scale scores by 1.2. CONCLUSIONS Midwifery is a profession with a high sense of spirituality. However, professional belonging, love of the profession and professional development positively affect midwives' levels of compassion. Improving midwives' feelings of belonging and their professional development will also contribute to the quality of maternal and infant health.