This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. high resistance to M. cannonballus. A total of four accessions, 'K134068', 'K133069', 'Wondae' and 'PI 414723', showing resistance to both pathogens were selected as candidates for melon rootstock. Yield and quality of fruits harvested from 'Earl's elite' (Muskmelon, Reticulatus Group) grafted onto the selected melon rootstocks were found comparable to or better than those of non-grafted melons.Nearly negligible incidence of fruit fermentation was observed when 'Homerunstar' (Honeydew type, Inodorus Group) was grafted with the selected melon rootstocks, unlike when it was grafted onto 'Shintozwa' (Cucurbita spp.) rootstock. The selected melon accessions with resistance to Fusarium wilt and Monosporascus root rot are considered to be potential and valuable genetic resources for breeding program of melon.