Leachate is a complex wastewater produced through the decomposition and of waste in landfills. Little is known about the method of leachate modified oxidation disinfection of this study was conducted to investigate the possibility of using modified oxidation to remove coliform bacteria from the leachate. This was an experimental study conducted on the leachate of an urban compost plant. The experiments were performed in 0, 20, 40, 60, 80 min, with ozone concentration of 0 and 5 g hG the copper nanoparticles during 80 min which removed 98% of coliform form the sample. Increasing the process time leads to increase of the percentage of coliform bacteria elimination. An increase in the concentration of both ozone and the copper nanoparticles increased the removal rate to 98%. It can be concluded that ozonation process with the copper nanoparticles has a good performance in the removal of coliform bacteria from waste leachate.