Abstract. Parkinson's disease (PD) is a progressive neurodegenerative disorder assumed to involve dierent areas of CNS and PNS. In PD patients and in primates with experimental Parkinsonism indicating that retinal dopamine deciency is an important factor in the pathogenesis of PD visual dysfunction. Visual signs and symptoms of PD may include defects in eye movement, pupillary function, and in more complex visual tasks. In this study, we evaluated the areas involved in visual cortex in PD by diusion tensor imaging to assess the structural change in PD.