Background: Negative Pressure Wound Therapy (NPWT) is considered an effective treatment in facilitating the healing of chronic wounds. However, its effect remains inconsistent, which allows for further investigation. Objective: This study aimed to assess the effectiveness of the NPWT program in improving the management of chronic wound healing. Design: Systematic review and meta-analysis was used. Data Sources: The search strategy ranged from 2016 to 2021 in PubMed, CINAHL, ProQuest, and ScienceDirect. Review Methods: Risk of bias was done based on the Risk of Bias 2.0 guideline using RevMan 5.4.1, and meta-analysis was done using Jeffreys’s Amazing Statistics Program (JASP) software version 0.16.3. Critical appraisal of the included articles was done according to Joanna Briggs Institute’s (JBI) appraisal checklist. Results: A total of 15 articles were included, with 3,599 patients with chronic wounds. There was no publication bias in this study seen from the results of the Egger’s test value of 0.447 (p >0.05), symmetrical funnel plot, and fail-safe N of 137. However, heterogeneity among studies was present, with I2 value of 66.7%, Q = 41.663 (p <0.001); thus, Random Effect (RE) model was used. The RE model showed a significant positive effect of the NPWT on chronic wound healing, with z = 3.014, p = 0.003, 95% CI 0.085 to 0.400. The observed effects include decreased rate of surgical site infection, controlled inflammation, edema, and exudate, as well as increased tissue with varying forest plot size, as demonstrated by the small effect size (ES = 0.24, 95% CI -0.26 to 0.79, p <0.05). Conclusion: The analysis results show that the standard low pressure of 80-125 mmHg could improve microcirculation and accelerate the healing process of chronic wounds. Therefore, applying the NPWT program could be an alternative to nursing interventions. However, it should be carried out by competent wound nurses who carry out procedure steps, implement general patient care, and give tips on overcoming device problems and evaluation. PROSPERO registration number: CRD42022348457

Diaper dermatitis is one of the most common dermatologic diseases in infants and toddler with high rate of incidence and prevalence. Diaper dermatitis occurs due to poor knowledge of giving care for infant and toddler skin. One of skin care to do infant and toddler with diaper dermatitis is apply olive oil. Olive oil is a herbal remedy with anti-inflammatory, analgesic, anti-microbial and anti-oxidant activities effects. The aim of this study was to analyze the effectiveness of the use olive oil on diaper dermatitis among infants and toddlers aged 0 to 36 months old. This was a quasy experimental study with one group pretest-posttest design with 40 samples in intervention group with total sampling. Subjects were follow up between June until August 2019. Diaper Dermatitis Severity Index Score was used to measure diaper dermatitis. To analyze and compare the data, frequency distribution, mean (standard deviation), variance analysis, and paired samples t tests were used. The results demonstrated a statistically significant difference with mean diaper dermatitis for pretest and posttest group. Apply olive oil was effective on diaper dermatitis than use standard care. Families have to be informed about the importance of a clean and dry diaper area and the frequency of diaper change. The use of olive oil has decreased the incidence of the disease. Olive oil can be an alternative treatment for diaper dermatitis     Abstrak Ruam popok adalah salah satu penyakit kulit yang paling umum dialami oleh bayi dan balitas dengan tingginya angka insidensi dan prevalensi. Ruam popok terjadi karena kurangnya pengetahuan dalam pemberian perawatan pada kulit bayi dan balita. Salah satu perawatan kulit pada bayi dan balita dengan ruam popok adalah pemberian minyak zaitun. Minyak zaitun merupakan suatu herbal yang dapat membantu dengan mempunyai efek anti inflamasi, analgesic, anti-mikroba dan antioksidan. Tujuan pada penelitian ini adalah untuk menganalisis efektivitas pemberian minyak zaitun terhadap ruam popok pada bayi dan balita berusia 0-36 bulan. Jenis penelitia adalah quasi eksperimen dengan desain satu kelompok pretest-posttest pada 40 responden melalui total sampling. Responden diteliti dari bulan Juni sampai Agustus 2019 Instrumen Diaper Dermatitis Severity Index Score digunakan dalam mengukur ruam popok. Untuk menganalisis dan membandingkan data, distribusi frekuensi, mean (standar deviasi), Paired t-test digunakan. Hasil penelitian menunjukkan bahwa adanya perbedaan yang signifikan secara statistik ruam popok pada kelompok pretest dan posttest. Pemberian minyak zaitun efektik terhadap ruam popok dibandingkan dengan perawatan standar. Keluarga diinformasikan tentang pentingnya kebersihan dan keringnya area popok dan frekuensi perubahan popok. Penggunaan minyak zaitun dapat menurunkan insidensi penyakit. Minyak zaitun dapat menjadi pengobatan alternative pada ruam popok.

Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus (DM) that can be slow to heal, result in repeated hospitalizations, require intense and costly treatment, and reduce the quality of life. The purpose of this study was to investigate the effect of foot exercises on wound healing in type 2 diabetic patients with a diabetic foot ulcer. Quasi-experimental study using before and after changes to wound healing in between February until May 2019.Thirty patients from an inpatient rooms with ulcers who met study criteria agreed to participate. Subjects were recruited by the researchers in the hospital where they received treatment. Data were collected using investigator-developed forms: patient information form and the diabetic foot exercises log. Patients in the intervention group received standard wound care and performed daily foot exercises for 3 week. Diabetic wound healing of the patients in the intervention were examined and measured at the 3rd weeks. To analyze and compare the data, frequency distribution, mean (standard deviation), and the paired samples t test were used. The mean of diabetic wound healing were 3.50, 2.90, and 2.40 in the study intervention group in 1st, 2nd, and 3rd weeks, respectively. Significant differences were found between diabetic wound healing in pre-test and post-test group (p=0.041). An important finding in this study was the DFU area decreased more in those who exercised more. Findings suggest foot exercises should be included in the treatment plan when managing patients with diabetic foot ulcers.     Abstrak Luka kaki diabetic adalah suatu komplikasi yang serius pada diabetes mellitus dimana dapat memperlambat penyembuhan, hospitalisasi berulang, membutuhkan pengobatan yang mahal dan menurunkan kualitas hidup. Tujuan penelitian ini adalah untuk mengetahui efek senam kaki terhadap penyembuhan luka pada pasien diabetes mellitus tipe 2. Jenis penelitian Quasi eksperimen digunakan untuk melihat perubahan sebelum dan sesudah penyembuhan luka dari Februari sampai Mei 2019. Tiga puluh pasien dari ruang inap dengan luka menjadi kriteria inklusi sebagai responden. Responden direkrut oleh peneliti di rumah sakit dimana pasien sedang menjalani perawatan. Pengumpulan data menggunakan kuesioner data demografi dan lembar observasi penyembuhan luka. Pasien akan diberikan latihan selama 3 minggu. Penyembuhan luka diabetic pada pasien akan dikaji dan diukur sampai minggu ke tiga. Untuk menganalisis dan membandingkan data, distribusi frekuensi, mean (standar deviasi), dan paired t test dilakukan. Mean penyembuhan luka diabetik diantaranya 3.50, 2.90 dan 2.40 pada kelompok intervensi pada minggu pertama, kedua, dan ketiga secara berurutan. Perbedaan signifikan penyembuhan luka diabetic antara kelompok pre-test dan post-test (p=0.041). Suatu temuan penting bahwa area luka kaki diabetic semakin menurun pada orang yang melakukan senam. Temuan ini juga senam kaki sebaiknya dimasukkan dalam rencana perawatan ketika merawat pasien dengan luka kaki diabetik.

Chronic Venous Leg Ulcers (CVLUs) are vascular diseases and require complex wound care from a patient, wound, health personnel and dressing factors. Cadexomer Iodine (CI) and Polyhexamethylene Biguanide (PHMB) are antimicrobial and broad-spectrum wound washing fluids. The uncontrolled infection will complicate wound healing due to bacteria or plankton from the biofilm stage to infection, which causes a long healing time. Purpose: to determine the effectiveness of the combination of Polyhexamethylene biguanide and Cadexomer Iodine on venous leg ulcer wound healing. Methods: This study is a case study using CVLUs as a sample, with pre-test and post-test designs, patients with CVLUs received topical antimicrobial CI and PHMB interventions on wounds for 7 weeks. The sample in this study used one sample with a pre-post treatment design for seven days.. The instrument uses the Bates Jensen Wound Assessment Tool. Results: The combination of CI and PHMB was shown to improve the healing of CVLUs by controlling bacterial infection in wounds. In the 2nd week, the wound was 26cm x 15cm, the slough was reduced, and the red base wound increased. In the 3rd week, the wound was stage 4, and the granulation increase was 75%. In the 7th treatment, the wound size scale increased 7cmx4cm, the wound became stage 2, and a significant increase in epithelialization was 75%. Conclusion: The combination of PHMB and CI has been shown to control infection at the biofilm stage to critical colonization, reduce odour and significantly control infection, and increase granulation and epithelialization in CVLUs

Nurses hold an important responsibility for maintaining patients’safety. It has been known that fatigue and sleepiness may result in errors with negative consequences for patient safety. The purpose of this study was to examine the relationship between fatigue and excessive daytime sleepiness among nurses. This research design is descriptive correlation. The total sample in this study was 36 nurses. This research was conducted at the Special Eye Hospital Medan. Sampling using purposive sampling. Data collection using the Three-Dimensional Work Fatigue Inventory (3D-WFI) and The Epworth Sleepiness Scale. Data analysis using the Chi-Square test. The results of this study indicate that the majority of nurses experience tired fatigue as many as 22 respondents (61.1%) compared to 14 respondents (38.9%) not tired. Chi Square test showed an association between fatigue and excessive daytime sleepiness (EDS) in nurses (P = 0.000 <α 0.05). This study recommends nurses to optimize the work hours of nurses to overcome daytime sleepiness, and for nurses to maintain conditions in order to avoid excessive sleepiness which can cause adverse event.