There are many causes of trauma such as traffic accidents, work accidents and falling from height. These patients require systematic management in post-traumatic evaluation, airway management, resuscitation, possible surgical procedures, intensive care follow-up and treatment. The nature of the trauma, post-traumatic uncontrolled bleeding, coagulation anomalies, hypothermia, shock and acidosis disrupts the normal homeostatic mechanism and is associated with poor clinical outcome. Other paradox in trauma patients is the necessity for emergency intervention with insufficient medical history information of the patient and unclear trauma type. In this review, it was aimed to discuss the general management and anesthesia management of patients with neurotrauma and thoracic trauma in the light of current guidelines.